When an inmate comes in with an entirely preventable illness, Max, Sharpe, and Iggy head directly to the source - Rikers Island. Meanwhile, Bloom struggles with her recovery, and Reynolds gets news that could change his life.
When Kapoor introduces a patient to Iggy's PTSD group, a creative treatment plans causes turmoil. Meanwhile, Sharpe discovers a long-kept secret regarding a patient that leads to trouble for Max and the board.
When a group of women on a retreat end up in the ED, Max gets some troubling information that could put a patient in jeopardy. Meanwhile, Sharpe and Kapoor work together to mend fences between two feuding sisters.
Max takes a chance on a new assistant and goes toe to toe with the board on a new plan. Meanwhile, Iggy struggles to figure out what is causing a unit-wide illness and Kapoor receives some shocking news.
Max invokes a hospital-wide census in effort to get to know the staff of New Amsterdam on a deeper level. Reynolds takes a leap of faith that lands him in hot water, and Dr. Castro extends her treatment plan to more patients in the hospital.
In the Season Two premiere, Max works to find a new normal three months after the catastrophic accident and the birth of his daughter. Kapoor grapples with the stigmas of aging, and Iggy has a successful day that inspires a life-changing idea. Meanwhile, Reynolds deals with an unreliable new intern.